Search Results - technology+classifications+%3e+antibodies

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Targeted Legumain-Cleavable Top1i ADC Platform

This technology introduces a legumain-cleavable antibody drug complex that delivers a topoisomerase inhibitor directly into tumor cells. Its short, polar linker design enables controlled intracellular release, improving targeting precision and therapeutic potential. In contrast to other related technologies, this invention employs low-potency Top1i...

Published: 4/28/2026 | Updated: 12/10/2025 | Inventor(s): Lawrence Tumey, Nicholas Bianchi, Victor Ojo

Keywords(s): Technologies

Category(s): Campus > Binghamton University, Technology Classifications > Antibodies, Technology Classifications > Therapeutics and Vaccines

A New Bioorthogonal Reaction

A fast, stable, versatile biomolecule coupling technology based on a bioorthogonal reaction that can occur at neutral pH and room temperature Background: “Click Chemistry” reactions are high yielding, wide in scope, create only byproducts that can be removed without chromatography, simple to perform, and can be conducted in easily removable...

Published: 3/4/2026 | Updated: 11/7/2019 | Inventor(s): Susan Bane Tuttle, Özlem Dilek, Kamalika Mukherjee

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Antibodies, Campus > Binghamton University