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Inhibitors for the Glutamine Transporter ASCT2

A portfolio of novel glutamine transporter ASCT2 inhibitors with affinities in the lower micromolar down to the nanomolar range. Background: Changes in cell metabolism support rapid growth and proliferation of tumor cells, resulting in increased reliance on the metabolism of amino acids such as glutamine (i.e., ‘glutamine addiction’)....

Published: 12/28/2023 | Inventor(s): Christof Grewer, Elias Ndaru, Yueyue Shi, Laura Zielewicz

Keywords(s): #SUNYresearch, Technologies

Category(s): Campus > Binghamton University, Technology Classifications > Therapeutics and Vaccines