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Traceless Protein–DNA Conjugation for Next-Gen Biotech
This invention introduces a fast, site-specific enzymatic method for attaching oligonucleotides to proteins with near-traceless precision, enabling cleaner, more functional conjugates for diagnostics, therapeutics, and nanotechnology. Background: Conventional methods for protein–oligonucleotide conjugation often suffer from slow reaction rates,...
Published: 9/26/2025
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Inventor(s):
Brian Callahan
,
Timothy Owen
Keywords(s):
#SUNYresearch
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Research Tools and Reagents
,
Campus > Binghamton University
Synthesis and Potential Uses of 2-(N-(2-(Fmoc)ethyl)-2-(6-(tert-butoxycarbonylamino)pyridin-3-yl)acetamido) Acetic Acid
Synthesis of peptide nucleic acids with modified nucleobases with high affinity to recognize and complex double-stranded RNA at physiologically relevant conditions Background: Compared to DNA, molecular recognition of double stranded RNA has received relatively little attention. Since it has been discovered that RNA can catalyze chemical reactions,...
Published: 8/21/2025
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Inventor(s):
Eriks Rozners
,
Thomas Zengeya
Keywords(s):
#SUNYresearch
,
Technologies
Category(s):
Technology Classifications > Research Tools and Reagents
,
Campus > Binghamton University
A New Bioorthogonal Reaction
A fast, stable, versatile biomolecule coupling technology based on a bioorthogonal reaction that can occur at neutral pH and room temperature Background: “Click Chemistry” reactions are high yielding, wide in scope, create only byproducts that can be removed without chromatography, simple to perform, and can be conducted in easily removable...
Published: 8/21/2025
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Inventor(s):
Susan Bane Tuttle
,
Özlem Dilek
,
Kamalika Mukherjee
Keywords(s):
#SUNYresearch
,
Technologies
Category(s):
Technology Classifications > Research Tools and Reagents
,
Technology Classifications > Screens and Assays
,
Technology Classifications > Antibodies
,
Campus > Binghamton University