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Traceless Protein–DNA Conjugation for Next-Gen Biotech

This invention introduces a fast, site-specific enzymatic method for attaching oligonucleotides to proteins with near-traceless precision, enabling cleaner, more functional conjugates for diagnostics, therapeutics, and nanotechnology. Background: Conventional methods for protein–oligonucleotide conjugation often suffer from slow reaction rates,...

Published: 11/12/2025 | Inventor(s): Brian Callahan, Timothy Owen

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Campus > Binghamton University

Stable RNA targeting using triple helix forming peptide nucleic acids

This invention introduces modified peptide nucleic acids that can recognize double-stranded RNA with high strength and sequence selectivity under physiological conditions. By enabling stable triple helix formation at neutral pH, these molecules overcome limitations of traditional approaches that require acidic environments. The technology opens new...

Published: 11/21/2025 | Inventor(s): Eriks Rozners, Thomas Zengeya

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Research Tools and Reagents, Campus > Binghamton University

A New Bioorthogonal Reaction

A fast, stable, versatile biomolecule coupling technology based on a bioorthogonal reaction that can occur at neutral pH and room temperature Background: “Click Chemistry” reactions are high yielding, wide in scope, create only byproducts that can be removed without chromatography, simple to perform, and can be conducted in easily removable...

Published: 11/12/2025 | Inventor(s): Susan Bane Tuttle, Özlem Dilek, Kamalika Mukherjee

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Antibodies, Campus > Binghamton University