Search Results - technology+classifications+%3e+biomedical+science+and+engineering

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Valve-on-a-chip microfluidic device for study of calcific aortic valve disease pathophysiology and drug targets. Background: Calcific aortic valve disease (CAVD) is the most common valvular heart disease in the aging population of the developed world. CAVD is a condition in which calcium deposits form in the aortic valve of the heart, narrowing...

Published: 12/29/2023 | Inventor(s): Gretchen Mahler, Pong-Yu Huang, Bruce Murray, Mei-Hsiu Chen, Melissa Mendoza

Keywords(s): Technologies

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering

Deep-penetrating Lidocaine Topical Gel

A new formulation of deep-penetrating lidocaine circumvents the need for painful injections. Background: Lidocaine is a local anesthetic commonly used prior to facial medical and cosmetic procedures, as well as before dental surgery. While lidocaine is very quick and effective at numbing the treatment area to avoid pain during the procedure, the...

Published: 12/28/2023 | Inventor(s): Anthony Di Pasqua, MENGWEI SUN

Keywords(s): Technologies, XCEED

Category(s): Campus > Binghamton University, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering

A Novel Biocompatible Cationic Liposome for the Delivery of Therapeutics

A biocompatible liposome transfection agent Background: Lipid-based non-viral systems for gene transfer have been widely investigated over the past few decades. Compared with viral vectors, liposomal vectors have the advantages of easier mass production and less immunogenicity. Dr. Anthony Di Pasqua has developed a novel biocompatible cationic liposome...

Published: 12/28/2023 | Inventor(s): Anthony Di Pasqua, MENGWEI SUN

Keywords(s):

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Biological Materials

Electronic-ECM: A Permeable Microporous Elastomer for an Advanced Bio-integrated Continuous Sensing Platform

Novel, self adhesive PDMS mesh inspired by the skin ECM for skin contact applications Background: Bio-integrated electronics are an emerging class of wearable devices capable of exploiting the native tissue’s mechanical and structural characteristics to provide an innate, seamless integration of soft electronics with biological tissue. These...

Published: 12/28/2023 | Inventor(s): Matthew Brown, Ahyeon Koh

Keywords(s): NSF I-Corps, XCEED

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering

Detection of Biomolecule Carbonylation

Rapid, accurate, and biocompatible oxidative damage detection probe Background: Oxidative stress is a characteristic of many disease states. One result of oxidative stress is an irreversible reaction of radicals with biomolecules that results in covalent addition of carbonyls to the biomolecules. The presence, location and amount of carbonylation...

Published: 12/28/2023 | Inventor(s): Susan Tuttle, Kamalika Mukherjee

Keywords(s):

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Materials and Chemicals

Vein Rolling Prevention Device

Device that prevents vein rolling to facilitate medical care Technology Overview: The phenomena of “rolling veins” occurs most commonly in the elderly. Cases where a medical professional requires multiple attempts to puncture a vein can lead to painful bruising over large regions around the puncture sites. As some nursing staff are not...

Published: 12/28/2023 | Inventor(s): Guy German, Emily Szabo, Julia Wilcox, Meranda Ruff, William McInerney

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Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering

High-Throughput Microfluidic Instrument for Constructing Custom Synthetic Vesicles with Asymmetric Membranes

Microfluidic device for constructing custom synthetic vesicles with controlled asymmetry Background: The ability to fabricate complex model membrane systems that are physiologically relevant to their natural systems has been a challenge in past decades. Conventional methods such as electroformation, gel hydration, bulk inverted emulsion, extrusion,...

Published: 12/28/2023 | Inventor(s): Li Lu, Sepehr Maktabi, Paul Chiarot, Jeffrey Schertzer

Keywords(s):

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Isothiocyanate-Containing Gel for Use Against Skin Cancer Alone or in Combination With Other Therapies

Novel treatment for skin cancer using a naturally-occurring compound Background: Approximately one in every five Americans will develop skin cancer during their lifetime. Most will develop non-melanoma skin cancer (NMSC), and the incidence of NMSC may increase by an estimated 50% by 2030, despite growing public awareness of the harmful effects of...

Published: 12/28/2023 | Inventor(s): Anthony Di Pasqua, Yi Shi, Ositomiwa Osipitan

Keywords(s):

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering

Genome Edited Tumor Cells as Anti Cancer Vaccines

This novel vaccine is comprised of inactivated whole tumor cells that lack the CD47 protein, making them more susceptible to immune cells in the body Background: The immune system is designed to defend our body against pathogens and dangerous invaders. However, cancer cells possess a plethora of immune evasion mechanisms in reaction to specific...

Published: 12/28/2023 | Inventor(s): Kaiming Ye, Sha Jin, Subhadra Jayaraman Rukmini

Keywords(s):

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Treatment of L-DOPA-induced Dyskinesia in Parkinson’s Disease

Repurposed antidepressant agents for treating levodopa-induced dyskinesia in Parkinson's disease Background: Dopamine replacement therapy with L-DOPA remains the gold-standard treatment for the crippling movement disruptions affecting >10 million Parkinson’s Disease patients worldwide. However, L-DOPA therapies, especially after...

Published: 12/29/2023 | Inventor(s): Christopher Bishop

Keywords(s): #SUNYresearch, #SUNYresearch, Technologies, XCEED

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

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