Search Results - technology+classifications+%3e+biomedical+science+and+engineering

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A new formulation of deep-penetrating lidocaine circumvents the need for painful injections. Background: Lidocaine is a local anesthetic commonly used prior to facial medical and cosmetic procedures, as well as before dental surgery. While lidocaine is very quick and effective at numbing the treatment area to avoid pain during the procedure, the...

Published: 8/21/2025 | Inventor(s): Anthony Di Pasqua, MENGWEI SUN

Keywords(s): Technologies, XCEED

Category(s): Campus > Binghamton University, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering

Detection of Biomolecule Carbonylation

Rapid, accurate, and biocompatible oxidative damage detection probe Background: Oxidative stress is a characteristic of many disease states. One result of oxidative stress is an irreversible reaction of radicals with biomolecules that results in covalent addition of carbonyls to the biomolecules. The presence, location and amount of carbonylation...

Published: 8/21/2025 | Inventor(s): Susan Tuttle, Kamalika Mukherjee

Keywords(s):

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Materials and Chemicals

Genome Edited Tumor Cells as Anti Cancer Vaccines

This novel vaccine is comprised of inactivated whole tumor cells that lack the CD47 protein, making them more susceptible to immune cells in the body Background: The immune system is designed to defend our body against pathogens and dangerous invaders. However, cancer cells possess a plethora of immune evasion mechanisms in reaction to specific...

Published: 8/21/2025 | Inventor(s): Kaiming Ye, Sha Jin, Subhadra Jayaraman Rukmini

Keywords(s):

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Treatment of L-DOPA-induced Dyskinesia in Parkinson’s Disease

Repurposed antidepressant agents for treating levodopa-induced dyskinesia in Parkinson's disease Background: Dopamine replacement therapy with L-DOPA remains the gold-standard treatment for the crippling movement disruptions affecting >10 million Parkinson’s Disease patients worldwide. However, L-DOPA therapies, especially after...

Published: 8/21/2025 | Inventor(s): Christopher Bishop

Keywords(s): #SUNYresearch, #SUNYresearch, Technologies, XCEED

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

Enzymatic Pyruvate Depletion as Adjunctive Therapy for the Treatment of Biofilm-Related Infections

Enzymatically driven pyruvate-depleting conditions enhance the ability of antimicrobial agents and/or the immune system to control the growth of microorganisms Background: A hallmark of biofilms is their extreme tolerance to antimicrobial agents, rendering infections by biofilms recalcitrant to conventional treatment therapies. This has brought...

Published: 8/21/2025 | Inventor(s): Karin Sauer, Amber Doiron, James Goodwine

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Microenvironments for Self-Assembly of Islet Organoids from Stem Cell Differentiation

Decellularized tissue-specific extracellular matrix and microenvironments for pancreatic islet organoid differentiation Background: Type 1 diabetes results from autoimmune destruction of β-cells, leading to incapable of maintaining normoglycemia in these patients. Although type 2 diabetes is caused by the peripheral resistance to insulin...

Published: 8/21/2025 | Inventor(s): Sha Jin, Kaiming Ye, Huanjing Bi

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Method and Composition for Biocatalytic Protein-Oligonucleotide Conjugation

Efficient and selective method to catalytically ligate a polypeptide to a nucleic acid in a single step Background: Site-specific selective protein modification procedures have been useful for oriented protein immobilization, studies of naturally occurring post-translational modifications, creating antibody-drug conjugates, introduction of fluorophores...

Published: 8/21/2025 | Inventor(s): Brian Callahan, Timothy Owen

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Campus > Binghamton University