Search Results - technology+classifications+%3e+biomedical+science+and+engineering

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Needle-Free Ultraflexible Liposome Gel for Deep, Long-Lasting Anesthesia

This ultraflexible liposome gel delivers lidocaine through the skin to provide deeper and longer-lasting local anesthesia without injections. By combining highly deformable vesicles with a stable gel matrix, the system enhances transdermal penetration, supports sustained release, and improves patient comfort. It offers a needle-free approach that outperforms...

Published: 11/14/2025 | Inventor(s): Anthony Di Pasqua, MENGWEI SUN

Keywords(s): Technologies, XCEED

Category(s): Campus > Binghamton University, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering

Detection of Biomolecule Carbonylation

Rapid, accurate, and biocompatible oxidative damage detection probe Background: Oxidative stress is a characteristic of many disease states. One result of oxidative stress is an irreversible reaction of radicals with biomolecules that results in covalent addition of carbonyls to the biomolecules. The presence, location and amount of carbonylation...

Published: 11/12/2025 | Inventor(s): Susan Tuttle, Kamalika Mukherjee

Keywords(s):

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Materials and Chemicals

Immune-Activated Genome-Edited Cancer Vaccines for Next-Generation Immunotherapy

This technology introduces a genome-edited whole-cell cancer vaccine engineered to remove key immune evasion signals such as CD47, enabling robust macrophage activation and enhanced antigen presentation. The edited, non-replicating tumor cells stimulate durable, systemic anti-tumor immunity with fewer off-target effects than antibody-based checkpoint...

Published: 11/21/2025 | Inventor(s): Kaiming Ye, Sha Jin, Subhadra Jayaraman Rukmini

Keywords(s):

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Dual-Action Therapy to Prevent L-DOPA-Induced Dyskinesia

This invention repurposes vilazodone, a serotonin reuptake inhibitor and 5-HT1A partial agonist, for dual-action therapy with L-DOPA to reduce Parkinson’s dyskinesia without diminishing motor benefits, offering a more effective long-term treatment strategy. Background: L-DOPA is the gold-standard treatment for Parkinson’s disease, but...

Published: 11/12/2025 | Inventor(s): Christopher Bishop

Keywords(s): #SUNYresearch, #SUNYresearch, Technologies, XCEED

Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

Enzymatic Pyruvate Depletion as Adjunctive Therapy for the Treatment of Biofilm-Related Infections

Enzymatically driven pyruvate-depleting conditions enhance the ability of antimicrobial agents and/or the immune system to control the growth of microorganisms Background: A hallmark of biofilms is their extreme tolerance to antimicrobial agents, rendering infections by biofilms recalcitrant to conventional treatment therapies. This has brought...

Published: 11/12/2025 | Inventor(s): Karin Sauer, Amber Doiron, James Goodwine

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Decellularized Matrix Technology for Functional, Vascularized Pancreatic Islet Organoids

This invention uses a detergent-free decellularized pancreatic extracellular matrix (dpECM) to direct human pluripotent stem cells into self-assembled, vascularized pancreatic islet organoids. By recreating the native pancreatic microenvironment, the technology promotes β-cell maturation, multicellular organization, and glucose-responsive insulin...

Published: 11/26/2025 | Inventor(s): Sha Jin, Kaiming Ye, Huanjing Bi

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University

Traceless Protein–DNA Conjugation for Next-Gen Biotech

This invention introduces a fast, site-specific enzymatic method for attaching oligonucleotides to proteins with near-traceless precision, enabling cleaner, more functional conjugates for diagnostics, therapeutics, and nanotechnology. Background: Conventional methods for protein–oligonucleotide conjugation often suffer from slow reaction rates,...

Published: 11/12/2025 | Inventor(s): Brian Callahan, Timothy Owen

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Campus > Binghamton University